Tips from our featured course
COPD: From the Pharmacist
Bronchodilators are the mainstay of maintenance treatment for COPD.
- Bronchodilators provide symptomatic relief to COPD patients with airflow obstruction
- Bronchodilators improve cough effectiveness and facilitate the clearing of secretions
Beta2-agonist and anticholinergic combination therapy is superior to beta2-agonist therapy alone. In contrast to asthma, COPD is treated more effectively with anticholinergics than beta2-agonists.
[COPD, Mod C, Pharmacologics]
COPD: Inhalers vs. Nebulizers
Drug delivery by a metered-dose inhaler (MDI) or dry powder inhaler (DPI) is preferable.
High doses of nebulized B2-agonists and anticholinergics singly or in combination can be used during exacerbations when the simplicity of administration is an advantage.
In stable disease there appears to be no significant difference in exercise performance between drugs administered through inhalers versus nebulizer.
Oral and parenteral administration is not recommended.
[COPD, Module C, Pharmacologics]